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PT-141 research peptide vial — bremelanotide, melanocortin-4 agonist
Individual Peptides 7 min read 2026-06-23

What Is PT-141? Melanocortin Peptide Research Guide

Last updated: 2026-06-23

Written by the AllMyPeptides Research Team

What Is PT-141?

PT-141 (international name bremelanotide) is a cyclic melanocortin-receptor agonist, structurally related to Melanotan-2, with activity at the melanocortin-4 receptor (MC4R).

Research use only. This material is supplied for in-vitro laboratory research. It is not a medicine and is not for human or veterinary consumption, administration, or therapeutic use.

How PT-141 Is Studied to Work

In research PT-141 is associated with central melanocortin-4 receptor signalling. The MC4R pathway is studied in neuroscience and physiology, distinct from peripheral vascular mechanisms.

Approved Use & Regulatory Status

As bremelanotide (brand Vyleesi), this molecule is FDA-approved in the US for a specific indication (hypoactive sexual desire disorder in certain adults) under medical supervision. It does not hold a UK marketing authorisation for general use. Research-grade 'PT-141' is not the approved product and is supplied for laboratory research only — not for human use.

Research Handling & Quality

As a lyophilised (freeze-dried) peptide it is typically stored frozen and reconstituted with bacteriostatic water for in-vitro work — see our reconstitution guide and storage guide. Identity and purity should be verified against a batch-matched Certificate of Analysis (COA) with HPLC and mass-spectrometry data. View pt-141 product details and COA.

Frequently Asked Questions

Is PT-141 approved in the UK?+
The related medicine bremelanotide (Vyleesi) is FDA-approved in the US for a specific indication, but research-grade PT-141 has no UK authorisation and is for laboratory use only.
What receptor does PT-141 act on?+
It is studied as a melanocortin-4 receptor (MC4R) agonist.
Is PT-141 the same as Melanotan-2?+
They are structurally related melanocortin agonists, but PT-141 (bremelanotide) is a distinct molecule with its own approved medical form (Vyleesi).

Products discussed in this guide are for research and laboratory use only. AllMyPeptides does not condone or support misuse of any research materials. Not for human or animal consumption.